German scientists discover new proteins provide ideas for cancer treatment The University of Bonn, Germany, published a communique saying that an international research team led by researchers at the university discovered a protein that can “switch” the immune system. Chronic inflammation caused by excessive response provides new ideas. On the one hand, the human immune system needs to respond in a timely manner when pathogens invade to eliminate intruders, and on the other hand, it cannot react excessively, causing damage to the body's own tissues. Regulatory T cells play a special role in maintaining the normal functioning of the immune system, which can avoid excessive immune response. The latest research found that a protein called "SATB1" plays a "switch" role in this immune regulation. It can turn regulatory T cells into offensive T cells and help kill cancer cells that suppress the immune system. On the other hand, suppressing the gene expression of this protein can restore the excessive response of the immune system causing chronic inflammation to normal levels. The researchers' tests on the experimental mice showed that implanting the gene encoding this protein in healthy mice upregulates the number of their immune cells, and the experimental mice will suffer from chronic enteritis. If the gene expression of this protein is inhibited, regulatory T cells in the mouse will dominate, and inflammation will not occur in the experimental mouse. Researchers say that the usual cancer treatment usually first completely suppresses the wrongly programmed immune system and allows the bone marrow to produce new immune cells, but this method has limited effect on many elderly patients. The newly discovered protein can transform the existing regulatory T cells of the patient's immune system into offensive T cells and help defeat cancer. However, there is still a long way to go before this therapy can be put into clinical use. Schultz, a professor at the University of Bonn who participated in the research, pointed out that this study found for the first time that the implantation of a gene can transform regulatory T cells into normal immune cells, indicating that although aggressive T cells and regulatory T cells are different Characteristics, but not as different types as previously thought, but can be achieved through the newly discovered protein conversion.

Home Decor Storage

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Ultimately, a home storage rack is an essential element of any well-organized home. With the right rack, you can easily store and access your belongings, making your home more functional and comfortable. Whether you choose a wire shelving unit, a wooden bookcase, or a wall-mounted storage rack, you'll be sure to find a storage solution that meets your needs and fits in with your home decor.

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