TGF-β1:

Transforming growth factor β1 (TGF-β1) is a polypeptide cell growth negative regulator related to the growth of various epithelial tumors discovered by Tuker et al. in 1984. It is widely involved in various pathophysiological processes in vivo, with inflammation, trauma, The occurrence and development of various diseases such as organ fibrosis are closely related, especially in the regulation and development of tumors. It has far-reaching significance for the study of tumors.

TGF-β2:

Like TGF-β1 and TGF-β3, TGF-β2 also plays an important role in cell proliferation, differentiation, embryonic development, extracellular matrix formation, bone formation and remodeling, and tumor suppression and metastasis. TGF-β2 has been shown to inhibit the growth of IL-2 dependent T cells and to inhibit immune surveillance in tumor development, thereby promoting tumor growth in an autocrine manner. TGF-β2 can affect the viability of killer cells and reduce the expression of IL-2, IL-6, IL-10, IFN-γ and other cytokines.

TGF-β3:

TGF-β3 stimulates the synthesis of extracellular matrix of target cells (fibroblasts, vascular endothelial cells, etc.) during tissue repair and accelerates vascularization, and promotes wound healing and reduces scar formation. TGF-β3 promotes morphogenesis during mammalian embryo development and plays an important role in spinal formation, limb germination, teething, facial bone formation and heart valve formation. TGF-β3 regulates bone formation and can affect adult bone regeneration. The study found that the serum concentration of TGF-β3 in patients with osteoporosis increased, and its level may reflect the decrease in TGF-β3 activity in bone tissue, thereby promoting the pathological process of osteoporosis.

What does Hengyuan tell you about TGF-β1 and TGF-β2?

Shanghai Hengyuan Bio has been focusing on scientific research since its establishment. TGF-β1, TGF-β2, TGF-β3 Elisa kit (for scientific research only) has obtained many scientific research advantages such as moderate price, fast delivery and excellent quality. The favor and support of friends, in order to better give back to customers, continue to provide scientific research units with better and more reliable scientific research products, help your scientific research, persist in looking into the future, continue to create products in the field of biology, you are welcome to call to discuss business!

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